Trump receives experimental antibody treatment

D

dukkha

Verified User
When a person is infected with a germ — a coronavirus, for example — the person's immune system creates proteins called antibodies tailor-made for that specific germ. Armed with those antibodies, the immune system can recognize the enemy in case it shows up again and fight it off.

Donated plasma is infused into patients to give an immediate boost to their immune system. There is anecdotal evidence it works.

But convalescent plasma relies on the altruism of blood donors, and blood donations cannot meet the demands of a pandemic

Monoclonal antibodies are made in a laboratory, designed to mimic the natural antibodies found in the body.

"Monoclonals are a refinement" of the convalescent plasma process, Gronvall said, "mass producing it as a purified form."

Convalescent plasma contains all of a person's antibodies to a variety of pathogens, not just the coronavirus. But in the lab, scientists can pinpoint specific antibodies and then manufacture them en mass
 
President Donald Trump has received an experimental drug following his diagnosis of Covid-19, the White House said Friday.

"As a precautionary measure, he received a single 8 gram dose of Regeneron's polyclonal antibody cocktail.
He completed the infusion without incident," Dr. Sean Conley, the president's physician, wrote in a memorandum.

Full coverage of the coronavirus outbreak

The drug cocktail is a combination of two so-called monoclonal antibodies. The treatment is meant to provide the body's immune system with a temporary, but immediate, boost to fight off the coronavirus.

Monoclonal antibodies (or, in this case, polyclonal because there are two in the cocktail) are made in a lab to mimic the body's natural antibodies. Antibodies act by recognizing specific germs — in this case, SARS-CoV-2, the virus that causes Covid-19 — and harnessing the immune system to fight them off.

The therapy, though still unproven, is considered by experts to be one of the most promising treatment options for the illness.
Regeneron confirmed it provided its drug to the president under what is called "compassionate use," through which the Food and Drug Administration allows access to experimental drugs outside of clinical trials for patients with a life-threatening condition or serious disease.
https://www.nbcnews.com/health/heal...ntibody-treatment-covid-19-diagnosis-n1241916
 
dukkha said:
When a person is infected with a germ — a coronavirus, for example — the person's immune system creates proteins called antibodies tailor-made for that specific germ. Armed with those antibodies, the immune system can recognize the enemy in case it shows up again and fight it off.

Donated plasma is infused into patients to give an immediate boost to their immune system. There is anecdotal evidence it works.

But convalescent plasma relies on the altruism of blood donors, and blood donations cannot meet the demands of a pandemic

Monoclonal antibodies are made in a laboratory, designed to mimic the natural antibodies found in the body.

"Monoclonals are a refinement" of the convalescent plasma process, Gronvall said, "mass producing it as a purified form."

Convalescent plasma contains all of a person's antibodies to a variety of pathogens, not just the coronavirus. But in the lab, scientists can pinpoint specific antibodies and then manufacture them en mass
Click to expand...

Doctor Nerdberg says the treatment didn't work.

Nerdberg said:
They gave him a drug cocktail that obviously did not work. He is being choppered out.
Click to expand...
 
Legion said:
Doctor Nerdberg says the treatment didn't work.
Click to expand...
lol..it's in clinical phase 3 ( like everything it seems) but has done a lot of good.

The other oddity is Pepcid for the stomach.
https://www.medpagetoday.com/infectiousdisease/covid19/88119
Use of famotidine in a small group of 83 patients was associated with a lower risk of in-hospital mortality and a combined outcome of death and intubation, reported Jeffrey Mather, MS, of Hartford Hospital in Connecticut, and colleagues.

Moreover, famotidine use was also associated with lower levels of serum markers indicating severe disease, the authors wrote in the American Journal of Gastroenterology.

Famotidine is a histamine-2 receptor antagonist. The authors noted the mechanism by which famotidine might improve COVID-19 outcomes is currently unknown, but hypothesized it might work via "inverse-agonism" of the histamine-2 receptor, which implies SARS-CoV-2 is "at least partially mediated by pathological histamine release," the authors said.
 
Didn't he sign an executive order recently regarding this type of treatment for older folks?
 
Damocles said:
Didn't he sign an executive order recently regarding this type of treatment for older folks?
Click to expand...

Right to Try Law -for compassionate use -expanded access
https://www.healthaffairs.org/do/10.1377/hblog20181024.111856/full/

In (Expanded access)EA, the treating doctor asks the company developing the desired investigational product for access, either for a single patient or for a group of patients. If the company agrees to provide the product for a single patient, a proposed treatment protocol is sent to the FDA for review. The agency permits almost all such requests, although some protocols are modified. Next, the proposed protocol goes to the Institutional Review Board (IRB) at the institution where the investigational product would be used for review and approval. When these steps have been completed (emergency requests are handled a bit differently), the patient may receive the investigational agent. Severe adverse events resulting from use of the investigational product must be reported to the FDA and the company that provided the product. RTT follows this same process, but it cuts out both FDA and IRB review of the protocol. It also eliminates the required reporting of severe adverse events to the FDA, except in certain circumstances. Importantly, neither EA nor RTT requires a company to provide the investigational product being requested, meaning that under Right to Try patients actually have only the “Right to Ask” — as they have had for years via EA.
 
Legion said:
Isn't it supposed to produce immediate results within 24 hours?

Doctor Nerdberg seems to think so.
Click to expand...

Apparently in testing it raises the antibodies to the same level of somebody who is 20 year old with COVID in about 24 hours or so. While it won't cure you in 24 hours, it gives you a fighting chance to kill the disease far more easily.
 
Damocles said:
Apparently in testing it raises the antibodies to the same level of somebody who is 20 year old with COVID in about 24 hours or so. While it won't cure you in 24 hours, it gives you a fighting chance to kill the disease far more easily.
Click to expand...

Is it possible that Doctor Nerdberg's analysis was unscientific, in your opinion?
 
Legion said:
Is it possible that Doctor Nerdberg's analysis was unscientific, in your opinion?
Click to expand...

LOL. I'd call it "hopeful" on his part. The reality is, the President walked to the helicopter without aid and doesn't appear to be in quite as dire straits as Nordberg seems to wishfully believe.
 
Damocles said:
LOL. I'd call it "hopeful" on his part. The reality is, the President walked to the helicopter without aid and doesn't appear to be in quite as dire straits as Nordberg seems to wishfully believe.
Click to expand...

The Interwebs are alight with leftists claiming/speculating/hoping that President Trump is actually near death.

If any of them pray, I don't doubt they are praying for whatever entity they think exists to smite the president down.
 
dukkha said:
President Donald Trump has received an experimental drug following his diagnosis of Covid-19, the White House said Friday.

"As a precautionary measure, he received a single 8 gram dose of Regeneron's polyclonal antibody cocktail.
He completed the infusion without incident," Dr. Sean Conley, the president's physician, wrote in a memorandum.

Full coverage of the coronavirus outbreak

The drug cocktail is a combination of two so-called monoclonal antibodies. The treatment is meant to provide the body's immune system with a temporary, but immediate, boost to fight off the coronavirus.

Monoclonal antibodies (or, in this case, polyclonal because there are two in the cocktail) are made in a lab to mimic the body's natural antibodies. Antibodies act by recognizing specific germs — in this case, SARS-CoV-2, the virus that causes Covid-19 — and harnessing the immune system to fight them off.

The therapy, though still unproven, is considered by experts to be one of the most promising treatment options for the illness.
Regeneron confirmed it provided its drug to the president under what is called "compassionate use," through which the Food and Drug Administration allows access to experimental drugs outside of clinical trials for patients with a life-threatening condition or serious disease.
https://www.nbcnews.com/health/heal...ntibody-treatment-covid-19-diagnosis-n1241916
Click to expand...

Looks like an act of desperation to me. What are they not telling everyone about Trump's health condition?
 
Damocles said:
LOL. I'd call it "hopeful" on his part. The reality is, the President walked to the helicopter without aid and doesn't appear to be in quite as dire straits as Nordberg seems to wishfully believe.
Click to expand...

He did seem healthy walking out. Still, this experimental drug treatment on POTUS seems risky compared to conventional treatments.
 
bleach-iv.jpg
 
dukkha said:
When a person is infected with a germ — a coronavirus, for example — the person's immune system creates proteins called antibodies tailor-made for that specific germ. Armed with those antibodies, the immune system can recognize the enemy in case it shows up again and fight it off.

Donated plasma is infused into patients to give an immediate boost to their immune system. There is anecdotal evidence it works.

But convalescent plasma relies on the altruism of blood donors, and blood donations cannot meet the demands of a pandemic

Monoclonal antibodies are made in a laboratory, designed to mimic the natural antibodies found in the body.

"Monoclonals are a refinement" of the convalescent plasma process, Gronvall said, "mass producing it as a purified form."

Convalescent plasma contains all of a person's antibodies to a variety of pathogens, not just the coronavirus. But in the lab, scientists can pinpoint specific antibodies and then manufacture them en mass
Click to expand...

How about an exorcism.
 
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